112 Results for "

Piper wightii Miq.

" in MedChemExpress (MCE) Product Catalog:
Products (112)

112 Results for "Piper wightii Miq." in MCE Product Catalog:

22
22 Publications Verification
Art. -Nr.: HY-107738
CAS. Nr.: 95975-55-6
Reinheit:  99.81%
Synonyms: Z/E-Guggulsterone
Guggulsterone is a plant sterol derived from the gum resin of the tree Commiphora wightii. Guggulsterone inhibits the growth of a wide variety of tumor cells and induces apoptosis through down regulation of antiapoptotic gene products (IAP1, xIAP, Bfl-1/A1, Bcl-2, cFLIP and survivin), modulation of cell cycle proteins (cyclin D1 and c-Myc), activation of caspases and JNK, inhibition of Akt . Guggulsterone, a farnesoid X receptor (FXR) antagonist, with IC50s of 24.06 μM and 39.05 μM for (-)-(E)-Guggulsterone (HY-N7781) and (Z)-Guggulsterone (HY-110066), respectively .
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3
3 Cited Publications
Art. -Nr.: HY-N2905
CAS. Nr.: 56121-42-7
Synonyms: Asperglaucide
Aurantiamide acetate (TMC-58A) is a selective and orally active cathepsin inhibitor isolated from Portulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of inflammatory diseases .
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2
2 Cited Publications
Art. -Nr.: HY-N2096
CAS. Nr.: 3155-48-4
Kavain is a class of kavalactone isolated from Piper methysticum, which has anxiolytic properties in animals and humans. Kavain positively modulated γ-Aminobutyric acid type A (GABAA) receptor .
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1
1 Cited Publications
Art. -Nr.: HY-126562
CAS. Nr.: 5950-12-9
Reinheit:  99.31%
Piperlonguminine is an alkaloid amide isolated from the Piper species. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibacterial activities .
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1
1 Cited Publications
Art. -Nr.: HY-N1887
CAS. Nr.: 1126-61-0
Synonyms: Hydroxychavicol; 4-Allylpyrocatechol
4-Allylcatechol (4-Allylpyrocatechol) is a xylan which has oral activity and can be isolated from the root of Piper taiwanense. 4-Allylcatechol has a strong inhibitory activity against collagen-induced platelet aggregation (IC50 = 5.3 μM). In addition, 4-Allylcatechol has anti-tuberculosis activity against Mycobacterium tuberculosis H37Rv (MIC = 27.6 μg/mL) .
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Art. -Nr.: HY-N0921
CAS. Nr.: 19902-91-1
Synonyms: (+)-Dihydromethysticin
Dihydromethysticin is an orally active natural active ingredient. Dihydromethysticin can be extracted from Piper methysticum. Dihydromethysticin inhibits carboxylesterase 1 (Ki = 68.2 μM) and CYP2A5. Dihydromethysticin upregulates NLRC3 and induces Apoptosis. Dihydromethysticin exhibits anticancer activity against colorectal cancer and lung adenoma .
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Art. -Nr.: HY-N3097
CAS. Nr.: 18836-52-7
Pellitorine is a bioactive natural amide compound. Pellitorine can competitively antagonize the activation of TRPV1 by Capsaicin (HY-10448), thereby reducing pain signal transmission. Pellitorine improves cognitive dysfunction by upregulating the BDNF-ERK1/2-CREB and Nrf2-HO-1 pathways. Pellitorine exerts anti-inflammatory and anti-sepsis effects by inhibiting the release of high mobility group protein B1 (HMGB1) and the expression of RAGE/TLR4. Pellitorine exerts its antithrombotic effect by prolonging the clotting time, inhibiting the activity of clotting factors and thrombin. Pellitorine inhibits lipid peroxidation and resists ferroptosis by upregulating GPX4 and DHODH. Pellitorine kills Aedes aegypti mosquito larvae by inhibiting V-type H⁺-ATPase and aquaporin 4 (AaAQP4). Pellitorine exhibits anti-cancer activity (e.g., leukemia and breast cancer) and has inhibitory effects on certain bacteria .
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Art. -Nr.: HY-N10663
CAS. Nr.: 95851-37-9
Kadsurenone is a lignan with specific antagonistic activity against platelet-activating factor. Kadsurenone can be derived from the stem of Piper kadsura .
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Art. -Nr.: HY-W088037
CAS. Nr.: 629-50-5
Tridecane is a short chain aliphatic hydrocarbon containing 13 carbon atoms. Tridecane is an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane is a stress compound released by the brown marmorated stink bugs stress compound .
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Art. -Nr.: HY-N2465
CAS. Nr.: 495-85-2
Methylsticin is a kavalactone isolated from the Piper methysticum . Methylsticin exhibit osteoclast formation inhibitory activity .
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Art. -Nr.: HY-W088037S
CAS. Nr.: 121578-12-9
Tridecane-d28 is the deuterium labeled Tridecane . Tridecane is a short chain aliphatic hydrocarbon containing 13 carbon atoms. Tridecane is an volatile oil component isolated from essential oil of Piper aduncum L. Tridecane is a stress compound released by the brown marmorated stink bugs stress compound .
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Art. -Nr.: HY-121909
CAS. Nr.: 136-72-1
Target:  

Bacterial

Forschungsgebiete:  

Infection

Piperic acid is a natural antioxidant and antibacterial agent. Piperic acid can be used in food preservation and human health .
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Art. -Nr.: HY-N0701A
CAS. Nr.: 133-05-1
Asarinin is a extract lignan from Asarum sieboldii Miq., mainly produced in roots of this herb .
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Art. -Nr.: HY-W022390
CAS. Nr.: 25173-72-2
3-(3,4,5-Trimethoxyphenyl)propanoic acid is found in herbs and spices. 3-(3,4,5-Trimethoxyphenyl)propanoic acid is a constituent of Piper longum (long pepper) and Piper retrofractum (Javanese long pepper).
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Art. -Nr.: HY-N3915
CAS. Nr.: 28178-92-9
Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities .
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Art. -Nr.: HY-N10743
CAS. Nr.: 54794-74-0
Pipercide is an amide of piper nigrum fruits. Pipercide has larvicidal activity to mosquito. Pipercide acts on the nervous system and induces repetitive discharge on the central nerve cord. Pipercide can be used as an insecticide .
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Art. -Nr.: HY-N11529
CAS. Nr.: 133462-30-3
9-Methoxyaristolactam I is a natural product that can be isolated from the roots of Asarum sieboldii Miq. var. Seoulense Nakai .
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Art. -Nr.: HY-N3987
CAS. Nr.: 111843-10-8
Hancinone C (compound 2) is a natural product that can be found in Piper hancei .
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Art. -Nr.: HY-N0144B
CAS. Nr.: 30511-77-4
Isochavicine is an alkaloids that can be isolated from Piper retrofractum. Isochavicine inhibits the seedling growth of cress with I50 values of 11 μM .
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Art. -Nr.: HY-204591
CAS. Nr.: 84929-41-9
Target:  

Drug Derivative

Forschungsgebiete:  

Others

Black pepper oleoresin is a substance extracted from the pepper plant (Piper nigrum), which has aroma, spiciness, and bioactive components. It is widely used in food, health products, cosmetics, and daily chemical products.
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